Poseida Therapeutics Provides Update on Phase 1 Study of P-BCMA-101 CAR-T Product Candidate at the 2018 American Society of Hematology Annual Meeting

SAN DIEGO – Dec. 3, 2018 – Poseida Therapeutics Inc., a clinical-stage biopharmaceutical company leveraging proprietary non-viral gene engineering technologies to create life-saving therapeutics, today provided an update on the ongoing Phase 1 clinical trial of its autologous P-BCMA-101, a chimeric antigen receptor T-cell (CAR-T) product candidate in relapsed/refractory multiple myeloma, during an oral presentation at the 2018 American Society of Hematology (ASH) Annual Meeting. As of the data cutoff date, 23 patients had been treated across five dosing cohorts with no dose limiting toxicities observed, including two patients in cohort five who had been dosed with more than one billion (1000 x 10e6) CAR-T cells each. All patients in each of the five cohorts had responded to P-BCMA-101 and showed improved markers of disease.