Novan Announces Leadership Adjustments and Business Update

• Aligns existing talent and experience with next phase

• Accelerates broadening the application of the science

• Intends regulatory follow up with regard to SB204 for acne

• Resource alignment to near term focus

• Strengthening the balance sheet an important focus

Novan, Inc. (“the Company” or “Novan”) (NASDAQ:NOVN) today announced adjustments to its executive leadership team with immediate effect. These actions will accelerate a repositioning of the business and align talent and experience with the near and intermediate term phase of the Company.